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BMCBI
2010
126views more  BMCBI 2010»
15 years 6 months ago
Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data
Background: The enumeration of tetrameric and other sequence motifs that are positively or negatively correlated with in vivo antisense DNA effects has been a useful addition to t...
Donald M. Gray, Carla W. Gray, Byong-Hoon Yoo, Tzu...
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2007
154views more  BMCBI 2007»
15 years 6 months ago
Classification of heterogeneous microarray data by maximum entropy kernel
Background: There is a large amount of microarray data accumulating in public databases, providing various data waiting to be analyzed jointly. Powerful kernel-based methods are c...
Wataru Fujibuchi, Tsuyoshi Kato
BMCBI
2008
94views more  BMCBI 2008»
15 years 6 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
BMCBI
2008
176views more  BMCBI 2008»
15 years 6 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick