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BMCBI
2007
145views more  BMCBI 2007»
15 years 6 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
BMCBI
2007
140views more  BMCBI 2007»
15 years 6 months ago
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure in
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...
BMCBI
2007
112views more  BMCBI 2007»
15 years 6 months ago
Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis
Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
BMCBI
2007
106views more  BMCBI 2007»
15 years 6 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
BMCBI
2007
128views more  BMCBI 2007»
15 years 6 months ago
Userscripts for the Life Sciences
Background: The web has seen an explosion of chemistry and biology related resources in the last 15 years: thousands of scientific journals, databases, wikis, blogs and resources ...
Egon L. Willighagen, Noel M. O'Boyle, Harini Gopal...
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