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BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Gene prioritization and clustering by multi-view text mining
Background: Text mining has become a useful tool for biologists trying to understand the genetics of diseases. In particular, it can help identify the most interesting candidate g...
Shi Yu, Léon-Charles Tranchevent, Bart De M...
BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
BMCBI
2010
96views more  BMCBI 2010»
15 years 6 months ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
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