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NAR
2006
108views more  NAR 2006»
15 years 6 months ago
GLIDA: GPCR-ligand database for chemical genomic drug discovery
G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is a novel public GPCR...
Yasushi Okuno, Jiyoon Yang, Kei Taneishi, Hiroaki ...
NAR
2006
120views more  NAR 2006»
15 years 6 months ago
SuperNatural: a searchable database of available natural compounds
Although tremendous effort has been put into synthetic libraries, most drugs on the market are still 10 natural compounds or derivatives thereof. There are encyclopaedias of natur...
Mathias Dunkel, Melanie Füllbeck, Stefanie Ne...
SIGIR
2008
ACM
15 years 6 months ago
Separate and inequal: preserving heterogeneity in topical authority flows
Web pages, like people, are often known by others in a variety of contexts. When those contexts are sufficiently distinct, a page's importance may be better represented by mu...
Lan Nie, Brian D. Davison
ANOR
2005
93views more  ANOR 2005»
15 years 6 months ago
Looking Ahead with the Pilot Method
The pilot method as a meta-heuristic is a tempered greedy method aimed at obtaining better solutions while avoiding the greedy trap by looking ahead for each possible choice. Repea...
Stefan Voß, Andreas Fink, Cees Duin
AEI
2004
150views more  AEI 2004»
15 years 6 months ago
Ant colony optimization techniques for the vehicle routing problem
This research applies the meta-heuristic method of ant colony optimization (ACO) to an established set of vehicle routing problems (VRP). The procedure simulates the decision-maki...
John E. Bell, Patrick R. McMullen