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BMCBI
2006
240views more  BMCBI 2006»
15 years 6 months ago
Statistical analysis of real-time PCR data
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...
206
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BMCBI
2006
127views more  BMCBI 2006»
15 years 6 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
BMCBI
2006
146views more  BMCBI 2006»
15 years 6 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2006
88views more  BMCBI 2006»
15 years 6 months ago
Effect of various normalization methods on Applied Biosystems expression array system data
Background: DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based m...
Catalin C. Barbacioru, Yulei Wang, Roger D. Canale...
BMCBI
2006
128views more  BMCBI 2006»
15 years 6 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...