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ISCI
2007
115views more  ISCI 2007»
15 years 6 months ago
Compressed histograms with arbitrary bucket layouts for selectivity estimation
Selectivity estimation is an important step of query optimization in a database management system, and multidimensional histogram techniques have proved promising for selectivity ...
Dennis Fuchs, Zhen He, Byung Suk Lee
BMCBI
2005
127views more  BMCBI 2005»
15 years 6 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
BMCBI
2005
89views more  BMCBI 2005»
15 years 6 months ago
An empirical analysis of training protocols for probabilistic gene finders
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
William H. Majoros, Steven Salzberg
JCB
2007
144views more  JCB 2007»
15 years 6 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
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