Selectivity estimation is an important step of query optimization in a database management system, and multidimensional histogram techniques have proved promising for selectivity ...
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...