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216
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BMCBI
2006
119views more  BMCBI 2006»
15 years 7 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2006
109views more  BMCBI 2006»
15 years 7 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
BMCBI
2006
164views more  BMCBI 2006»
15 years 7 months ago
Evaluation of clustering algorithms for gene expression data
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...
Susmita Datta, Somnath Datta
218
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BMCBI
2006
127views more  BMCBI 2006»
15 years 7 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
213
Voted
BMCBI
2006
143views more  BMCBI 2006»
15 years 7 months ago
Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Eric D. Scheeff, Philip E. Bourne