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188
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BMCBI
2008
123views more  BMCBI 2008»
15 years 7 months ago
PocketMatch: A new algorithm to compare binding sites in protein structures
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
Kalidas Yeturu, Nagasuma Chandra
CSDA
2006
169views more  CSDA 2006»
15 years 6 months ago
Generalized structured additive regression based on Bayesian P-splines
Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Ba...
Andreas Brezger, Stefan Lang
221
Voted
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
197
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NPL
2006
137views more  NPL 2006»
15 years 6 months ago
Minimal Structure of Self-Organizing HCMAC Neural Network Classifier
The authors previously proposed a self-organizing Hierarchical Cerebellar Model Articulation Controller (HCMAC) neural network containing a hierarchical GCMAC neural network and a ...
Chih-Ming Chen, Yung-Feng Lu, Chin-Ming Hong
BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz