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BMCBI
2006
152views more  BMCBI 2006»
15 years 6 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
BMCBI
2006
165views more  BMCBI 2006»
15 years 6 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
Taking U out, with two nucleases?
Background: REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are ...
I. Saira Mian, Elizabeth A. Worthey, Reza Salavati
BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
BMCBI
2006
154views more  BMCBI 2006»
15 years 6 months ago
Agile methods in biomedical software development: a multi-site experience report
Background: Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully ...
David W. Kane, Moses M. Hohman, Ethan G. Cerami, M...