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BMCBI
2010
100views more  BMCBI 2010»
15 years 6 months ago
Using genomic signatures for HIV-1 sub-typing
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
Aridaman Pandit, Somdatta Sinha
BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
BMCBI
2008
155views more  BMCBI 2008»
15 years 6 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2010
106views more  BMCBI 2010»
15 years 6 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2008
137views more  BMCBI 2008»
15 years 6 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
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