24451 search results - page 4694 / 4891 » Research methods in information |
181
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BMCBI
2007
15 years 6 months ago
2007
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
164
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BMCBI
2007
15 years 6 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
163
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BMCBI
2008
15 years 6 months ago
2008
Background: The availability of sequences from whole genomes to reconstruct the tree of life has the potential to enable the development of phylogenomic hypotheses in ways that ha...
177
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BMCBI
2008
15 years 6 months ago
2008
Background: Keyword searching through PubMed and other systems is the standard means of retrieving information from Medline. However, ad-hoc retrieval systems do not meet all of t...
158
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BMCBI
2008
15 years 6 months ago
2008
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...