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BMCBI
2010
165views more  BMCBI 2010»
15 years 6 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
A Web-based and Grid-enabled dChip version for the analysis of large sets of gene expression data
Background: Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible f...
Luca Corradi, Marco Fato, Ivan Porro, Silvia Scagl...
BMCBI
2008
143views more  BMCBI 2008»
15 years 6 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus
BMCBI
2008
99views more  BMCBI 2008»
15 years 6 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
Disambiguation of biomedical text using diverse sources of information
Background: Like text in other domains, biomedical documents contain a range of terms with more than one possible meaning. These ambiguities form a significant obstacle to the aut...
Mark Stevenson, Yikun Guo, Robert J. Gaizauskas, D...
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