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BMCBI
2006
142views more  BMCBI 2006»
15 years 6 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2006
153views more  BMCBI 2006»
15 years 6 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
EC
2006
195views ECommerce» more  EC 2006»
15 years 6 months ago
Automated Global Structure Extraction for Effective Local Building Block Processing in XCS
Learning Classifier Systems (LCSs), such as the accuracy-based XCS, evolve distributed problem solutions represented by a population of rules. During evolution, features are speci...
Martin V. Butz, Martin Pelikan, Xavier Llorà...
BMCBI
2007
128views more  BMCBI 2007»
15 years 6 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
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