The state of the practice in object-oriented software development has moved beyond reuse of code to reuse of conceptual structures such as design patterns. This paper draws attenti...
Mutation-based Evolutionary Algorithms, also known as Evolutionary Programming (EP) are commonly applied to Artificial Neural Networks (ANN) parameters optimization. This paper pre...
Kristina Davoian, Alexander Reichel, Wolfram-Manfr...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...