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ICSE
2007
IEEE-ACM
16 years 16 days ago
Agility and Experimentation: Practical Techniques for Resolving Architectural Tradeoffs
This paper outlines our experiences with making architectural tradeoffs between performance, availability, security, and usability, in light of stringent cost and time-to-market c...
T. C. Nicholas Graham, Rick Kazman, Chris Walmsley
WOTUG
2008
15 years 7 months ago
Solving the Santa Claus Problem: a Comparison of Various Concurrent Programming Techniques
Abstract. The Santa Claus problem provides an excellent exercise in concurrent programming and can be used to show the simplicity or complexity of solving problems using a particul...
Jason Hurt, Jan Bækgaard Pedersen
PPOPP
2006
ACM
16 years 10 days ago
Performance characterization of molecular dynamics techniques for biomolecular simulations
Large-scale simulations and computational modeling using molecular dynamics (MD) continues to make significant impacts in the field of biology. It is well known that simulations...
Sadaf R. Alam, Jeffrey S. Vetter, Pratul K. Agarwa...
QEST
2005
IEEE
15 years 12 months ago
Fluid Flow Approximation of PEPA models
In this paper we present a novel performance analysis technique for large-scale systems modelled in the stochastic process algebra PEPA. In contrast to the well-known approach of ...
Jane Hillston
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...