Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Recently, more attention is paid to the researches and practices on how to use software architecture in software maintenance and evolution to reduce their complexity and cost. The ...
Commercial-off-the-shelf (COTS) software tends to be cheap, reliable, and functionally powerful due to its large user base. It has thus become highly desirable to incorporate COTS ...
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...