6568 search results - page 1185 / 1314 » Reducing the Complexity of Reductions |
190
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BMCBI
2010
15 years 6 months ago
2010
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
157
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BMCBI
2010
15 years 6 months ago
2010
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
187
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BMCBI
2008
15 years 6 months ago
2008
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
179
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BMCBI
2008
15 years 6 months ago
2008
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
208
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BMCBI
2006
15 years 6 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...