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» Reconstruction of Ancestral Genomic Sequences Using Likeliho...
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NAR
2000
120views more  NAR 2000»
15 years 5 months ago
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions bas...
Ross A. Overbeek, Niels Larsen, Gordon D. Pusch, M...
ISMB
2000
15 years 7 months ago
UTR Reconstruction and Analysis Using Genomically Aligned EST Sequences
Zhengyan Kan, Warren Gish, Eric C. Rouchka, Jarret...
WEA
2007
Springer
114views Algorithms» more  WEA 2007»
16 years 6 hour ago
Improving Tree Search in Phylogenetic Reconstruction from Genome Rearrangement Data
Abstract. A major task in evolutionary biology is to determine the ancestral relationships among the known species, a process generally referred as phylogenetic reconstruction. In ...
Fei Ye, Yan Guo, Andrew Lawson, Jijun Tang
BIOINFORMATICS
2004
83views more  BIOINFORMATICS 2004»
15 years 5 months ago
Haplotypes histories as pathways of recombinations
Motivation: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are...
Nadia El-Mabrouk, Damian Labuda
WABI
2001
Springer
15 years 10 months ago
A Chemical-Distance-Based Test for Positive Darwinian Selection
There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting p...
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Sham...