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BMCBI
2010
62views more  BMCBI 2010»
15 years 6 months ago
Forward-time simulation of realistic samples for genome-wide association studies
Background: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic...
Bo Peng, Christopher I. Amos
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...
BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
COGSCI
2010
82views more  COGSCI 2010»
15 years 6 months ago
Language Acquisition Meets Language Evolution
Recent research suggests that language evolution is a process of cultural change, in which linguistic structures are shaped through repeated cycles of learning and use by domain-g...
Nick Chater, Morten H. Christiansen