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ICCSA
2004
Springer
15 years 11 months ago
High Throughput in-silico Screening against Flexible Protein Receptors
We report results for the in-silico screening of a database of 10000 flexible compounds against various crystal structures of the thymidine kinase receptor complexed with 10 know...
Holger Merlitz, Wolfgang Wenzel
HAIS
2009
Springer
15 years 11 months ago
Hybrid Evolutionary Algorithm for Solving Global Optimization Problems
Differential Evolution (DE) is a novel evolutionary approach capable of handling non-differentiable, non-linear and multi-modal objective functions. DE has been consistently ranked...
Radha Thangaraj, Millie Pant, Ajith Abraham, Youak...
HIM
1997
Springer
162views Multimedia» more  HIM 1997»
15 years 10 months ago
Probabilistic Logical Information Retrieval for Content, Hypertext, and Database Querying
Classical retrieval models support content-oriented searching for documents using a set of words as data model. However, in hypertext and database applications we want to consider...
Thomas Rölleke, Markus Blömer
TREC
2004
15 years 7 months ago
Can We Get A Better Retrieval Function From Machine?
The quality of an information retrieval system heavily depends on its retrieval function, which returns a similarity measurement between the query and each document in the collect...
Weiguo Fan, Wensi Xi, Edward A. Fox, Li Wang
BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang