: The prediction of the binding free energy between a ligand and a protein is an important component in the virtual screening and lead optimization of ligands for drug discovery. T...
We present an algorithm, Hierarchical ISOmetric SelfOrganizing Map (H-ISOSOM), for a concise, organized manifold representation of complex, non-linear, large scale, high-dimension...
Collision detection in geometrically complex scenes is crucial in physical simulations and real time applications. Works based on spatial hierarchical structures have been propose...
Let D be a weighted directed graph cellularly embedded in a surface of genus g, orientable or not, possibly with boundary. We describe algorithms to compute a shortest non-contrac...
This paper investigates the problem of time-optimum movement planning in two and three dimensions for a point robot which has bounded control velocity through a set of n polygonal...