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BIBE
2010
IEEE
144views Bioinformatics» more  BIBE 2010»
15 years 8 months ago
Knowledge-Guided Docking of Flexible Ligands to SH2 Domain Proteins
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling and regulation. In this work, we applied a three-stage knowledg...
Haiyun Lu, Shamima Banu Bte Sm Rashid, Hao Li, Wee...
BMCBI
2008
117views more  BMCBI 2008»
15 years 7 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
JUCS
2008
118views more  JUCS 2008»
15 years 7 months ago
Enhancements of Meeting Information Management and Application for Knowledge Access and Learning Activities
: Communication processes have become increasingly important in modern working life. Organizations invest a surprisingly high amount of financial resources and employee work time i...
Christian Gütl
IJCINI
2007
139views more  IJCINI 2007»
15 years 7 months ago
AURELLIO: A Cognitive Computational Knowledge Representation Theory
: Cognitive informatics (CI) studies the natural intelligence and internal information processing mechanisms of the brain, as well as the processes involved in perception and cogni...
Mehdi Najjar, André Mayers
BCB
2010
140views Bioinformatics» more  BCB 2010»
15 years 2 months ago
Guiding belief propagation using domain knowledge for protein-structure determination
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Ameet Soni, Craig A. Bingman, Jude W. Shavlik