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BMCBI
2006
122views more  BMCBI 2006»
15 years 6 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
FOCS
2007
IEEE
16 years 1 months ago
Parameterized Proof Complexity
We propose a proof-theoretic approach for gaining evidence that certain parameterized problems are not fixedparameter tractable. We consider proofs that witness that a given prop...
Stefan S. Dantchev, Barnaby Martin, Stefan Szeider
ECBS
2006
IEEE
122views Hardware» more  ECBS 2006»
16 years 26 days ago
Customer-oriented Development of Complex Distributed Systems
Complex and distributed systems are more and more common. Hardware is going from strength to strength and is embedded in high performance peer-to-peer networks mostly. The task of...
Ivonne Erfurth
ICALP
2004
Springer
16 years 5 days ago
The Black-Box Complexity of Nearest Neighbor Search
We define a natural notion of efficiency for approximate nearest-neighbor (ANN) search in general n-point metric spaces, namely the existence of a randomized algorithm which answ...
Robert Krauthgamer, James R. Lee
ECBS
1996
IEEE
93views Hardware» more  ECBS 1996»
15 years 11 months ago
A Methodology for Designing and Dimensioning Critical Complex Computing Systems
It is widely recognized that real-time,fault-tolerant and distributed computing technologies play a key role in the deployment of many current andfuture (civilian or Defense) crit...
Gérard Le Lann