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ISBMS
2010
Springer
16 years 5 days ago
A Theoretical Model for RF Ablation of Kidney Tissue and Its Experimental Validation
Radio-frequency (RF) ablation is a minimal invasive thermal therapy, currently considered as an alternative to surgery to eradicate small solid kidney tumors. Our aim is to underst...
Mihaela Pop, Sean R. H. Davidson, Mark Gertner, Mi...
ISMB
1994
15 years 8 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
BMCBI
2010
113views more  BMCBI 2010»
15 years 7 months ago
A classification model for distinguishing copy number variants from cancer-related alterations
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
Irina Ostrovnaya, Gouri Nanjangud, Adam B. Olshen
196
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BMCBI
2008
111views more  BMCBI 2008»
15 years 7 months ago
Comparative optimism in models involving both classical clinical and gene expression information
Background: In cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: r...
Caroline Truntzer, Delphine Maucort-Boulch, Pascal...
BMCBI
2007
216views more  BMCBI 2007»
15 years 7 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos