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BMCBI
2008
136views more  BMCBI 2008»
15 years 7 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2006
99views more  BMCBI 2006»
15 years 7 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
92views more  BMCBI 2006»
15 years 7 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
CORR
2010
Springer
204views Education» more  CORR 2010»
15 years 5 months ago
Predictive State Temporal Difference Learning
We propose a new approach to value function approximation which combines linear temporal difference reinforcement learning with subspace identification. In practical applications...
Byron Boots, Geoffrey J. Gordon