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» Predicting protein function from domain content
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BMCBI
2005
93views more  BMCBI 2005»
15 years 6 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
BMCBI
2007
157views more  BMCBI 2007»
15 years 6 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
ISDA
2006
IEEE
16 years 1 days ago
From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway
The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions wit...
Sandhya Shenoy, B. Jayaram, N. Latha, Pooja Narang...
GECCO
2007
Springer
165views Optimization» more  GECCO 2007»
16 years 5 days ago
Peptide detectability following ESI mass spectrometry: prediction using genetic programming
The accurate quantification of proteins is important in several areas of cell biology, biotechnology and medicine. Both relative and absolute quantification of proteins is often d...
David C. Wedge, Simon J. Gaskell, Simon J. Hubbard...
BMCBI
2007
113views more  BMCBI 2007»
15 years 6 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...