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BMCBI
2007
106views more  BMCBI 2007»
15 years 6 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
BMCBI
2010
128views more  BMCBI 2010»
15 years 6 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BMCBI
2008
135views more  BMCBI 2008»
15 years 6 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
IJNSEC
2006
96views more  IJNSEC 2006»
15 years 6 months ago
A Memory Symptom-based Virus Detection Approach
The widespread use of the Internet has caused computer security to become an important issue. Currently, antivirus software is the primary mechanism that prevents computers from t...
Hsien-Chou Liao, Yi-Hsiang Wang
JCB
2008
159views more  JCB 2008»
15 years 6 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther