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BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
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JC
2008
128views more  JC 2008»
15 years 6 months ago
Lattice rule algorithms for multivariate approximation in the average case setting
We study multivariate approximation for continuous functions in the average case setting. The space of d variate continuous functions is equipped with the zero mean Gaussian measu...
Frances Y. Kuo, Ian H. Sloan, Henryk Wozniakowski
BMCBI
2005
93views more  BMCBI 2005»
15 years 6 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2005
122views more  BMCBI 2005»
15 years 6 months ago
A neural strategy for the inference of SH3 domain-peptide interaction specificity
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...
Enrico Ferraro, Allegra Via, Gabriele Ausiello, Ma...