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BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
CORR
2010
Springer
259views Education» more  CORR 2010»
15 years 6 months ago
Community Detection in Networks: The Leader-Follower Algorithm
Natural networks such as those between humans observed through their interactions or biological networks predicted based on various experimental measurements contain a wealth of i...
Devavrat Shah, Tauhid Zaman
ALMOB
2006
106views more  ALMOB 2006»
15 years 6 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
BMCBI
2005
112views more  BMCBI 2005»
15 years 6 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...