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ISMB
1998
15 years 8 months ago
Modeling Protein Homopolymeric Repeats: Possible Polyglutamine Structural Motifs for Huntington's Disease
Wedescribe a prototype system (Poly-X) for assisting an expert user in modelingprotein repeats. Poly-X reduces the large numberof degrees of freedomrequired to specify a protein m...
Richard H. Lathrop, Malcolm S. Casale, Douglas J. ...
ISMB
1993
15 years 8 months ago
Knowledge-Based Generation of Machine-Learning Experiments: Learning with DNA Crystallography Data
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman
BIOSYSTEMS
2007
103views more  BIOSYSTEMS 2007»
15 years 7 months ago
A design framework to model retinas
Neuro-engineering is providing biomedical engineers with technology to interface the nervous system, which is useful to create prosthetic devices to palliate sensorial or motor di...
Christian A. Morillas, Samuel F. Romero, Antonio M...
CORR
2010
Springer
174views Education» more  CORR 2010»
15 years 7 months ago
Hybrid Numerical Solution of the Chemical Master Equation
We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the ...
Thomas A. Henzinger, Maria Mateescu, Linar Mikeev,...
BMCBI
2006
105views more  BMCBI 2006»
15 years 7 months ago
Integrative investigation of metabolic and transcriptomic data
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Pinar Pir, Betül Kirdar, Andrew Hayes, Z. Ils...