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» Perspectives on Systems Biology
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SAC
2009
ACM
16 years 1 months ago
GTfold: a scalable multicore code for RNA secondary structure prediction
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
ISCA
2007
IEEE
196views Hardware» more  ISCA 2007»
16 years 1 months ago
Anton, a special-purpose machine for molecular dynamics simulation
The ability to perform long, accurate molecular dynamics (MD) simulations involving proteins and other biological macromolecules could in principle provide answers to some of the ...
David E. Shaw, Martin M. Deneroff, Ron O. Dror, Je...
BIBE
2006
IEEE
184views Bioinformatics» more  BIBE 2006»
16 years 1 months ago
A Language Modeling Text Mining Approach to the Annotation of Protein Community
This paper discusses an ontology based language modeling text mining approach to the annotation of protein community. Communities appear to play an important role in the functional...
Xiaodan Zhang, Daniel Duanqing Wu, Xiaohua Zhou, X...
NIPS
1997
15 years 8 months ago
Computing with Action Potentials
Most computational engineering based loosely on biology uses continuous variables to represent neural activity. Yet most neurons communicate with action potentials. The engineerin...
John J. Hopfield, Carlos D. Brody, Sam T. Roweis
BMCBI
2010
154views more  BMCBI 2010»
15 years 7 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg