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BMCBI
2010
122views more  BMCBI 2010»
15 years 6 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2010
102views more  BMCBI 2010»
15 years 6 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2008
117views more  BMCBI 2008»
15 years 6 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2006
106views more  BMCBI 2006»
15 years 6 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer
BMCBI
2010
108views more  BMCBI 2010»
15 years 6 months ago
iGTP: A software package for large-scale gene tree parsimony analysis
Background: The ever-increasing wealth of genomic sequence information provides an unprecedented opportunity for large-scale phylogenetic analysis. However, species phylogeny infe...
Ruchi Chaudhary, Mukul S. Bansal, André Weh...