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BMCBI
2007
143views more  BMCBI 2007»
15 years 7 months ago
RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
Yair Horesh, Tirza Doniger, Shulamit Michaeli, Ron...
BMCBI
2010
88views more  BMCBI 2010»
15 years 7 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2008
147views more  BMCBI 2008»
15 years 7 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...
BMCBI
2006
82views more  BMCBI 2006»
15 years 7 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BMCBI
2007
142views more  BMCBI 2007»
15 years 6 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...