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BMCBI
2004
177views more  BMCBI 2004»
15 years 6 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
JSS
2008
122views more  JSS 2008»
15 years 5 months ago
Traffic-aware stress testing of distributed real-time systems based on UML models using genetic algorithms
This report presents a model-driven, stress test methodology aimed at increasing chances of discovering faults related to network traffic in Distributed Real-Time Systems (DRTS). T...
Vahid Garousi, Lionel C. Briand, Yvan Labiche
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
15 years 5 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen
TCOM
2011
130views more  TCOM 2011»
15 years 1 months ago
Indirect Reciprocity Game Modelling for Cooperation Stimulation in Cognitive Networks
—In cognitive networks, since nodes generally belong to different authorities and pursue different goals, they will not cooperate with others unless cooperation can improve their...
Yan Chen, K. J. Ray Liu
WWW
2006
ACM
16 years 7 months ago
Knowledge modeling and its application in life sciences: a tale of two ontologies
High throughput glycoproteomics, similar to genomics and proteomics, involves extremely large volumes of distributed, heterogeneous data as a basis for identification and quantifi...
Satya Sanket Sahoo, Christopher Thomas, Amit P. Sh...