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BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2008
93views more  BMCBI 2008»
15 years 6 months ago
Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Guillaume Launay, Thomas Simonson
FGCS
2006
74views more  FGCS 2006»
15 years 6 months ago
A performance model of non-deterministic particle transport on large-scale systems
In this work we present a predictive analytical model that encompasses the performance and scaling characteristics of a nondeterministic particle transport application, MCNP (Mont...
Mark M. Mathis, Darren J. Kerbyson, Adolfy Hoisie
CORR
2007
Springer
135views Education» more  CORR 2007»
15 years 6 months ago
AMIEDoT: An annotation model for document tracking and recommendation service
The primary objective of document annotation in whatever form, manual or electronic is to allow those who may not have control to original document to provide personal view on inf...
Charles A. Robert
JCB
2006
129views more  JCB 2006»
15 years 6 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes