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BMCBI
2005
152views more  BMCBI 2005»
15 years 6 months ago
Ranking the whole MEDLINE database according to a large training set using text indexing
Background: The MEDLINE database contains over 12 million references to scientific literature, ut 3/4 of recent articles including an abstract of the publication. Retrieval of ent...
Brian P. Suomela, Miguel A. Andrade
BMCBI
2005
122views more  BMCBI 2005»
15 years 6 months ago
Computational verification of protein-protein interactions by orthologous co-expression
Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
Itay Tirosh, Naama Barkai
BMCBI
2005
113views more  BMCBI 2005»
15 years 6 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2005
94views more  BMCBI 2005»
15 years 6 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2005
135views more  BMCBI 2005»
15 years 6 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
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