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BMCBI
2006
75views more  BMCBI 2006»
15 years 6 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
BMCBI
2006
146views more  BMCBI 2006»
15 years 6 months ago
A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...
BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
244
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BMCBI
2006
94views more  BMCBI 2006»
15 years 6 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...
168
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BSL
2006
114views more  BSL 2006»
15 years 6 months ago
Schemata: The Concept of Schema in the History of Logic
Schemata have played important roles in logic since Aristotle's Prior Analytics. The syllogistic figures and moods can be taken to be argument schemata as can the rules of the...
John Corcoran
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