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BMCBI
2004
144views more  BMCBI 2004»
15 years 6 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BMCBI
2004
117views more  BMCBI 2004»
15 years 6 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
BMCBI
2004
105views more  BMCBI 2004»
15 years 6 months ago
eL-DASionator: an LDAS upload file generator
Background: The Distributed Annotation System (DAS) allows merging of DNA sequence annotations from multiple sources and provides a single annotation view. A straightforward way t...
Vincent Nègre, Christoph Grunau
BMCBI
2004
128views more  BMCBI 2004»
15 years 6 months ago
Comparing transformation methods for DNA microarray data
Background: When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed ...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2004
139views more  BMCBI 2004»
15 years 6 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
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