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BMCBI
2006
123views more  BMCBI 2006»
15 years 6 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger
GRID
2008
Springer
15 years 6 months ago
Can Economics-based Resource Allocation Prove Effective in a Computation Marketplace?
Several companies offer computation on demand for a fee. More companies are expected to enter this business over the next decade, leading to a marketplace for computation resource...
Kevin L. Mills, Christopher Dabrowski
BMCBI
2006
158views more  BMCBI 2006»
15 years 6 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2006
148views more  BMCBI 2006»
15 years 6 months ago
Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
Veronica Vinciotti, Xiaohui Liu, Rolf Turk, Emile ...
142
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BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
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