12841 search results - page 2226 / 2569 » PL-detective: experiences and results |
197
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BMCBI
2004
15 years 6 months ago
2004
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
170
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BMCBI
2004
15 years 6 months ago
2004
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
194
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BMCBI
2004
15 years 6 months ago
2004
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
186
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BMCBI
2004
15 years 6 months ago
2004
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
217
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BMCBI
2004
15 years 6 months ago
2004
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...