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BMCBI
2008
129views more  BMCBI 2008»
15 years 6 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2008
107views more  BMCBI 2008»
15 years 6 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
BMCBI
2008
159views more  BMCBI 2008»
15 years 6 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
CCR
2008
91views more  CCR 2008»
15 years 6 months ago
Serial experiments online
Current network protocols must comply with rigid interfaces and rules of behavior to fit into well defined, vertical protocol stacks. It is difficult for network designers to offe...
Juan J. Ramos-Muñoz, Lidia Yamamoto, Christ...