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182
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BMCBI
2010
15 years 6 months ago
2010
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
170
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BMCBI
2006
15 years 6 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
177
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MP
2002
15 years 6 months ago
2002
UOBYQA is a new algorithm for general unconstrained optimization calculations, that takes account of the curvature of the objective function, F say, by forming quadratic models by ...
205
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MP
2010
15 years 5 months ago
2010
Abstract. We present a null-space primal-dual interior-point algorithm for solving nonlinear optimization problems with general inequality and equality constraints. The algorithm a...
173
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PVLDB
2010
15 years 5 months ago
2010
The dramatic proliferation of sophisticated networks has resulted in a growing need for supporting effective querying and mining methods over such large-scale graph-structured da...