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134
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BMCBI
2007
15 years 6 months ago
2007
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
163
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BMCBI
2008
15 years 6 months ago
2008
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
169
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BMCBI
2007
15 years 6 months ago
2007
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
135
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BMCBI
2007
15 years 6 months ago
2007
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
176
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BMCBI
2007
15 years 6 months ago
2007
The bio-ontology community falls into two camps: first we have biology domain experts, who actually hold the knowledge we wish to capture in ontologies; second, we have ontology s...