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BMCBI
2010
107views more  BMCBI 2010»
15 years 6 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...
INFORMATICALT
2006
89views more  INFORMATICALT 2006»
15 years 6 months ago
Investigation of Examples of E-Education Environment for Scientific Collaboration and Distance Graduate Studies, Part 1
The objective is to investigate two emerging information technologies in graduate studies and scientific cooperation. Internet is the first technology. The open source is the secon...
Jonas Mockus
BMCBI
2005
130views more  BMCBI 2005»
15 years 6 months ago
MiMiR: a comprehensive solution for storage, annotation and exchange of microarray data
Background: The generation of large amounts of microarray data presents challenges for data collection, annotation, exchange and analysis. Although there are now widely accepted f...
Mahendra Navarange, Laurence Game, Derek Fowler, V...
JCB
2007
198views more  JCB 2007»
15 years 6 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III