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» On the need for statistical timing analysis
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BMCBI
2008
202views more  BMCBI 2008»
15 years 6 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2006
121views more  BMCBI 2006»
15 years 6 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
IDA
2008
Springer
15 years 6 months ago
Estimating the depth of anesthesia using fuzzy soft computation applied to EEG features
Estimating the depth of anesthesia (DOA) is still a challenging area in anesthesia research. The objective of this study was to design a fuzzy rule based system which integrates el...
V. Esmaeili, Amin Assareh, M. B. Shamsollahi, Moha...
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...