2740 search results - page 434 / 548 » On the importance and challenges of FOSD |
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BIOINFORMATICS
2006
15 years 6 months ago
2006
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
190
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BMCBI
2006
15 years 6 months ago
2006
Background: Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretica...
214
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BMCBI
2006
15 years 6 months ago
2006
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
168
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BMCBI
2006
15 years 6 months ago
2006
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
162
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BMCBI
2006
15 years 6 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...