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» On the expressiveness of interaction
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CIARP
2009
Springer
16 years 29 days ago
Analysis of the GRNs Inference by Using Tsallis Entropy and a Feature Selection Approach
Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Fabrício Martins Lopes, Evaldo A. de Olivei...
KBSE
2007
IEEE
16 years 20 days ago
Scalable automatic test data generation from modeling diagrams
We explore the automatic generation of test data that respect constraints expressed in the Object-Role Modeling (ORM) language. ORM is a popular conceptual modeling language, prim...
Yannis Smaragdakis, Christoph Csallner, Ranjith Su...
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
BMCBI
2008
202views more  BMCBI 2008»
15 years 6 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
98views more  BMCBI 2008»
15 years 6 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang