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BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
98views more  BMCBI 2006»
15 years 6 months ago
Scanning sequences after Gibbs sampling to find multiple occurrences of functional elements
Background: Many DNA regulatory elements occur as multiple instances within a target promoter. Gibbs sampling programs for finding DNA regulatory elements de novo can be prohibiti...
Kannan Tharakaraman, Leonardo Mariño-Ram&ia...
CAD
2006
Springer
15 years 6 months ago
A unified subdivision approach for multi-dimensional non-manifold modeling
This paper presents a new unified subdivision scheme that is defined over a k-simplicial complex in n-D space with k 3. We first present a series of definitions to facilitate top...
Yu-Sung Chang, Hong Qin
CSDA
2006
84views more  CSDA 2006»
15 years 6 months ago
Performing hypothesis tests on the shape of functional data
We explore different approaches for performing hypothesis tests on the shape of a mean function by developing general methodologies both, for the often assumed, i.i.d. error struc...
Gareth M. James, Ashish Sood
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
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