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BMCBI
2006
147views more  BMCBI 2006»
15 years 6 months ago
Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Alex Lewin, Ian C. Grieve
BMCBI
2006
125views more  BMCBI 2006»
15 years 6 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
BMCBI
2006
78views more  BMCBI 2006»
15 years 6 months ago
Subfamily logos: visualization of sequence deviations at alignment positions with high information content
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...
Eric Beitz
BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BMCBI
2006
115views more  BMCBI 2006»
15 years 6 months ago
The accuracy of several multiple sequence alignment programs for proteins
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
Paulo A. S. Nuin, Zhouzhi Wang, Elisabeth R. M. Ti...
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