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BIOINFORMATICS
2006
15 years 6 months ago
2006
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
189
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FSS
2008
15 years 6 months ago
2008
The grade of membership (GoM) model uses fuzzy sets as memberships of each individual to extreme profiles (or classes) on the likelihood function of multivariate multinomial distr...
167
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BMCBI
2006
15 years 6 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
164
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BMCBI
2006
15 years 6 months ago
2006
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
180
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BMCBI
2006
15 years 6 months ago
2006
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...